{"id":35651,"date":"2022-06-11T20:01:10","date_gmt":"2022-06-11T17:01:10","guid":{"rendered":"https:\/\/elantmaelmasry.com\/?p=35651"},"modified":"2022-06-11T20:01:51","modified_gmt":"2022-06-11T17:01:51","slug":"%d8%ac%d9%85%d8%a7%d9%84-%d8%b4%d8%b9%d8%a8%d8%a7%d9%86-%d8%a3%d8%ae%d9%8a%d8%b1%d9%8b%d8%a7-%d9%8a%d9%85%d9%83%d9%86-%d8%a7%d9%84%d8%b4%d9%81%d8%a7%d8%a1-%d9%85%d9%86-%d8%a7%d9%84%d8%b3%d8%b1%d8%b7","status":"publish","type":"post","link":"https:\/\/elantmaelmasry.com\/?p=35651","title":{"rendered":"\u062c\u0645\u0627\u0644 \u0634\u0639\u0628\u0627\u0646: \u0623\u062e\u064a\u0631\u064b\u0627 \u064a\u0645\u0643\u0646 \u0627\u0644\u0634\u0641\u0627\u0621 \u0645\u0646 \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u062a\u0645\u0627\u0645\u064b\u0627 \u0628\u062f\u0648\u0646 \u0643\u064a\u0645\u0627\u0648\u064a"},"content":{"rendered":"

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\n\u064a\u0633\u062a\u0637\u064a\u0639 \u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u0628\u0627\u0644\u0639\u0644\u0645 \u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0631 \u0641\u064a \u062d\u0631\u0628\u0647 \u0639\u0644\u0649 \u0623\u062e\u0637\u0631 \u0645\u0631\u0636 \u0639\u0644\u0649 \u0648\u062c\u0647 \u0627\u0644\u0628\u0633\u064a\u0637\u0629 \u0648\u0627\u0644\u0630\u064a \u0623\u0648\u062f\u0649 \u0628\u062d\u064a\u0627\u0629 \u0627\u0644\u0645\u0644\u0627\u064a\u064a\u0646 \u0648\u062e\u0644\u0642 \u062c\u0631\u0627\u062d\u0627 \u0639\u0645\u064a\u0642\u0629 \u0641\u064a \u0642\u0644\u0648\u0628 \u0623\u0633\u0631\u0647\u0645 \u0648\u0623\u062d\u0628\u0627\u0628\u0647\u0645..<\/strong>
\n\u0623\u0648\u0644 \u062f\u0648\u0627\u0621 \u0641\u0649 \u0627\u0644\u062a\u0627\u0631\u064a\u062e \u064a\u0634\u0641\u0649 \u0645\u0646 \u0645\u0631\u0636 \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0628\u0646\u0633\u0628\u0629 100% !!!!!!!!!! \u0627\u064a\u0648\u0648\u0648\u0648\u0648\u0648\u0648\u0629 . \u0632\u0649 \u0645\u0627 \u0642\u0631\u0627\u062a \u0643\u062f\u0629 \u0628\u0627\u0644\u0636\u0628\u0637 . \u0634\u0641\u0627\u0621 \u0628\u0646\u0633\u0628\u0629 100%\u060c \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0645\u0639\u062c\u0632\u0629 \u0627\u0644\u0644\u0649 \u0627\u0633\u0645\u0647 Dostarlimab \u0648\u0627\u0633\u0645\u0647 \u0627\u0644\u062a\u062c\u0627\u0631\u0649 \u0627\u0644\u0627\u0634\u0647\u0631 Jemperli\u060c \u0643\u0639\u0627\u062f\u062a\u0646\u0627 \u062e\u0644\u0648\u0646\u0627 \u0646\u0628\u0633\u0637 \u0627\u0644\u0627\u0645\u0648\u0631 . \u0627\u0644\u062f\u0648\u0627\u0621 \u0622\u062e\u0631\u0647 Mab \u064a\u0628\u0642\u0649 \u0639\u0631\u0641\u0646\u0627 \u0627\u0646\u0647 Monoclonal Antibody \u0648\u0637\u0627\u0644\u0645\u0627 \u0647\u0648 \u062c\u0633\u0645 \u0645\u0636\u0627\u062f \u064a\u0628\u0642\u0649 \u0647\u0627\u064a\u0634\u062a\u063a\u0644 \u0639\u0644\u0649 \u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0648\u0628\u0643\u062f\u0629 \u0646\u0642\u062f\u0631 \u0646\u0642\u0648\u0644 \u0627\u0646\u0647 Immunotherapy\u00bb<\/strong><\/p>\n

\u0648\u0623\u0634\u0627\u0631: \u00ab\u0627\u0644\u0640 Antibody \u0645\u062d\u062a\u0627\u062c Antigen \u064a\u0634\u0628\u0643 \u0645\u0639\u0627\u0647 . \u0648\u0639\u0634\u0627\u0646 \u0643\u062f\u0629 \u0627\u0644\u062f\u0648\u0627\u0621 \u0628\u062a\u0627\u0639\u0646\u0627 \u0627\u0644\u0646\u0647\u0627\u0631\u062f\u0629 \u0628\u064a\u0634\u0628\u0643 \u0648\u064a\u0631\u062a\u0628\u0637 \u0645\u0639 \u0645\u0633\u062a\u0642\u0628\u0644 \u0627\u0633\u0645\u0647 PD-1 Receptor \u0648\u0647\u0646\u0627 PD \u0627\u062e\u062a\u0635\u0627\u0631 \u0644 Programmed Death \u0648\u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 \u062f\u0647 \u0645\u0648\u062c\u0648\u062f \u0639\u0644\u0649 \u0633\u0637\u062d T cells . \u0648\u0639\u0634\u0627\u0646 \u0646\u0641\u0647\u0645 \u0622\u0644\u064a\u0629 \u0639\u0645\u0644 \u0627\u0644\u062f\u0648\u0627\u0621 \u062f\u0647 \u0628\u062f\u0648\u0646 \u062a\u0639\u0642\u064a\u062f . \u064a\u0628\u0642\u0649 \u0644\u0627\u0632\u0645 \u0646\u0641\u0647\u0645 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 \u0627\u0644\u0644\u0649 \u0627\u0633\u0645\u0647 PD-1 Receptor \u062f\u0647 \u0648\u0638\u064a\u0641\u062a\u0647 \u0627\u064a\u0647 \u0628\u0627\u0644\u062a\u062d\u062f\u064a\u062f \u061f\u061f\u061f\u060c \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 \u062f\u0647 \u0628\u064a\u0631\u062a\u0628\u0637 \u0645\u0639 Ligands \u0648\u0639\u062f\u062f\u0647\u0645 2 . \u0648\u0627\u0633\u0627\u0645\u064a\u0647\u0645 \u0633\u0647\u0644\u0629 \u062c\u062f\u0649 \u00a0\u0648\u0627\u062d\u062f \u0627\u0633\u0645\u0647 PD-L1 \u0648\u0627\u0644\u062b\u0627\u0646\u0649 \u0627\u0633\u0645\u0647 PD-L2 . \u0644\u0645\u0627 \u0627\u0644 Ligands \u0633\u0648\u0627\u0621 1 \u0627\u0648 2 \u064a\u0631\u062a\u0628\u0637\u0648\u0627 \u0645\u0639 PD-1 Receptor \u0647\u0627\u064a\u0645\u0646\u0639\u0648\u0627 Proliferation of T cells \u0648\u0647\u0627\u064a\u0645\u0646\u0639\u0648\u0627 Cytokine Production from T cells \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u0649 \u0647\u0627\u064a\u0639\u0645\u0644\u0648\u0627 Inhibition of the immune System \u0648\u0628\u0643\u062f\u0629 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0648\u0631\u0645 \u062a\u062a\u0643\u0627\u062b\u0631 \u0627\u0643\u062b\u0631 \u0644\u0627\u0646 \u0645\u0641\u064a\u0634 \u062c\u0647\u0627\u0632 \u0645\u0646\u0627\u0639\u0629 \u0647\u0627\u064a\u0642\u062f\u0631 \u064a\u0647\u0627\u062c\u0645\u0647\u0627\u00bb.<\/strong><\/p>\n

\u0648\u062a\u0627\u0628\u0639: \u00ab\u0627\u0644\u062f\u0648\u0627\u0621 \u0628\u062a\u0627\u0639\u0646\u0627 \u0628\u064a\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 \u062f\u0647 \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u0649 \u0628\u064a\u0645\u0646\u0639 \u0627\u0631\u062a\u0628\u0627\u0637 Ligands \u0628\u0647 \u0648\u0639\u0634\u0627\u0646 \u0643\u062f\u0629 \u0647\u0627\u062a\u062a\u0645\u0643\u0646 T cells \u0645\u0646 \u0627\u0644\u062a\u0643\u0627\u062b\u0631 \u0648\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0639\u062f\u062f \u0648\u0627\u0646\u062a\u0627\u062c Cytokines \u062a\u0647\u0627\u062c\u0645 \u0627\u0644\u0648\u0631\u0645 \u0648\u062a\u0645\u0646\u0639 \u062a\u0643\u0627\u062b\u0631\u0647 \u0648\u0627\u0646\u062a\u0634\u0627\u0631\u0647\u060c \u0627\u0644\u062f\u0648\u0627\u0621 \u062f\u0647 \u0627\u062e\u062f \u0627\u0628\u0631\u0648\u0641\u0627\u0644 2021 \u0644\u0639\u0644\u0627\u062c \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0631\u062d\u0645 \u0627\u0644\u0645\u062a\u0642\u062f\u0645 \u0627\u0648 Recurrent \u0648\u0639\u0627\u0645\u0644 \u0646\u062a\u0627\u0626\u062c \u0632\u0649 \u0627\u0644\u0641\u0644 . \u0648\u0628\u0639\u062f\u064a\u0646 \u0634\u0627\u0641\u0648\u0627 \u0627\u0646 \u0646\u0637\u0627\u0642 \u0639\u0645\u0644\u0647 \u0645\u0645\u0643\u0646 \u064a\u0648\u0633\u0639 \u0648\u064a\u062e\u0631\u062c \u0628\u0631\u0629 \u0627\u0644\u0631\u062d\u0645 \u0648\u064a\u0634\u062a\u063a\u0644 \u0639\u0644\u0649 \u0627\u0646\u0648\u0627\u0639 \u0622\u062e\u0631\u0649 \u0645\u0646 \u0627\u0644\u0627\u0648\u0631\u0627\u0645 \u0648\u062e\u0627\u0635\u0629 Solid Tumors\u060c \u0642\u0627\u0644 \u0644\u0643 \u062a\u0639\u0627\u0644\u0649 \u0646\u062c\u0631\u0628\u0647 \u0639\u0644\u0649 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0642\u0648\u0644\u0648\u0646\u060c \u0631\u0627\u062d\u0648\u0627 \u062c\u0627\u0628\u0648\u0627 12 \u0645\u0631\u064a\u0636 \u0633\u0631\u0637\u0627\u0646 \u0642\u0648\u0644\u0648\u0646 \u0645\u0631\u062d\u0644\u0629 \u062b\u0627\u0646\u064a\u0629 \u0648\u062b\u0627\u0644\u062b\u0629 . \u0628\u0639\u0636\u0647\u0645 \u0639\u0645\u0644 \u062c\u0631\u0627\u062d\u0629 \u0648\u0628\u0639\u0636\u0647\u0645 \u062e\u0636\u0639 \u0644\u0644\u0643\u064a\u0645\u0627\u0648\u0649 \u0648\u0644\u0644\u0627\u0634\u0639\u0627\u0639\u0649 \u0628\u062f\u0648\u0646 \u0641\u0627\u0626\u062f\u0629 \u062a\u0630\u0643\u0631 \u0648\u0645\u0627 \u0632\u0627\u0644 \u0627\u0644\u0648\u0631\u0645 \u0645\u062a\u0645\u0643\u0646\u0627 \u0645\u0646\u0647\u0645 \u0648\u0628\u062f\u0623 \u064a\u0646\u062a\u0634\u0631 \u0627\u0644\u0649 \u0627\u0644\u0639\u0642\u062f \u0627\u0644\u0644\u064a\u0645\u0641\u0627\u0648\u064a\u0629 \u0648\u0644\u0643\u0646 \u0644\u0645 \u064a\u0646\u062a\u0634\u0631 \u0627\u0644\u0649 \u0627\u0639\u0636\u0627\u0621 \u0627\u062e\u0631\u0649 \u062f\u0627\u062e\u0644 \u0627\u0644\u062c\u0633\u0645 \u0648\u062c\u0631\u0628\u0648\u0627 \u0639\u0644\u064a\u0647\u0645 \u0627\u0644 Dostarlimab \u0644\u0645\u062f\u0629 6 \u0634\u0647\u0648\u0631\u00bb<\/strong><\/p>\n

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